De Duve Institute

Research

Signal Transduction


Nucleoside Analogues in Leukaemia

Françoise Bontemps, Eric van de Neste
Mechanisms of action (activation, metabolism, apoptosis pathways,…) Mechanisms of resistance and search for improved efficacy



Protein Phosphorylation

Mark Rider
Control of cell function by insulin and AMP-activated protein kinase
Mass spectrometry



Growth Factor Receptor

Jean-Baptiste Demoulin
From signal transduction to human diseases



Cytokines in Immunity & Inflammation

Jean-Christophe Renauld
Analysis of IL-9 and IL-22 functions



Signal Transduction & Molecular Hematology

Stefan Constantinescu
Orientation-dependent signaling of cytokine receptor
Physiologic versus oncogenic signaling JAK2 V617F and human myeloproliferative diseases