
Dalet A, Robbins PF, Stroobant V, Vigneron N, Li YF, El-Gamil M, Hanada K, Yang JC, Rosenberg SA, Van den Eynde BJ.
An antigenic peptide produced by reverse splicing and double asparagine deamidation.
Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):E323-31. Epub 2011 Jun 13.
Ma W, Vigneron N, Chapiro J, Stroobant V, Germeau C, Boon T, Coulie PG, Van den Eynde BJ.
A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy.
Int J Cancer. 2011 Nov 15;129(10):2427-34. doi: 10.1002/ijc.25911. Epub 2011 Apr 20.
Guillaume B, Chapiro J, Stroobant V, Colau D, Van Holle B, Parvizi G, Bousquet-Dubouch MP, Théate I, Parmentier N, Van den Eynde BJ.
Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules.
Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18599-604. Epub 2010 Oct 11.
Parmentier N, Stroobant V, Colau D, de Diesbach P, Morel S, Chapiro J, van Endert P, Van den Eynde BJ.
Production of an antigenic peptide by insulin-degrading enzyme.
Nat Immunol. 2010 May;11(5):449-54. Epub 2010 Apr 4.
Dalet A, Vigneron N, Stroobant V, Hanada K, Van den Eynde BJ.
Splicing of distant peptide fragments occurs in the proteasome by transpeptidation and produces the spliced antigenic peptide derived from fibroblast growth factor-5.
J Immunol. 2010 Mar 15;184(6):3016-24. Epub 2010 Feb 12.
Warren EH, Vigneron NJ, Gavin MA, Coulie PG, Stroobant V, Dalet A, Tykodi SS, Xuereb SM, Mito JK, Riddell SR, Van den Eynde BJ.
An antigen produced by splicing of noncontiguous peptides in the reverse order.
Science. 2006 Sep 8;313(5792):1444-7.
Huijbers IJ, Krimpenfort P, Chomez P, van der Valk MA, Song JY, Inderberg-Suso EM, Schmitt-Verhulst AM, Berns A, Van den Eynde BJ.
An inducible mouse model of melanoma expressing a defined tumor antigen.
Cancer Res. 2006 Mar 15;66(6):3278-86.
Vigneron N, Stroobant V, Chapiro J, Ooms A, Degiovanni G, Morel S, van der Bruggen P, Boon T, Van den Eynde BJ.
An antigenic peptide produced by peptide splicing in the proteasome.
Science. 2004 Apr 23;304(5670):587-90. Epub 2004 Mar 4.
Ma W, Germeau C, Vigneron N, Maernoudt AS, Morel S, Boon T, Coulie PG, Van den Eynde BJ.
Two new tumor-specific antigenic peptides encoded by gene MAGE-C2 and presented to cytolytic T lymphocytes by HLA-A2.
Int J Cancer. 2004 May 1;109(5):698-702.
Uyttenhove C, Pilotte L, Théate I, Stroobant V, Colau D, Parmentier N, Boon T, Van den Eynde BJ.
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase.
Nat Med. 2003 Oct;9(10):1269-74. Epub 2003 Sep 21.
Schultz ES, Chapiro J, Lurquin C, Claverol S, Burlet-Schiltz O, Warnier G, Russo V, Morel S, Lévy F, Boon T, Van den Eynde BJ, van der Bruggen P.
The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome.
J Exp Med. 2002 Feb 18;195(4):391-9.
Probst-Kepper M, Stroobant V, Kridel R, Gaugler B, Landry C, Brasseur F, Cosyns JP, Weynand B, Boon T, Van Den Eynde BJ.
An alternative open reading frame of the human macrophage colony-stimulating factor gene is independently translated and codes for an antigenic peptide of 14 amino acids recognized by tumor-infiltrating CD8 T lymphocytes.
J Exp Med. 2001 May 21;193(10):1189-98.
Van den Eynde BJ, Morel S.
Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome.
Curr Opin Immunol. 2001 Apr;13(2):147-53. Review.
Morel S, Lévy F, Burlet-Schiltz O, Brasseur F, Probst-Kepper M, Peitrequin AL, Monsarrat B, Van Velthoven R, Cerottini JC, Boon T, Gairin JE, Van den Eynde BJ.
Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells.
Immunity. 2000 Jan;12(1):107-17.