Publications
Complete publication list (Pubmed search) :
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1. AMPK
AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.
Horman S, Morel N, Vertommen D, Hussain N, Neumann D, Beauloye C, El Najjar N, Forcet C, Viollet B, Walsh MP, Hue L, Rider MH.
J Biol Chem. 2008 Jul 4;283(27):18505-12. Epub 2008 Apr 21.
Effects of contraction and insulin on protein synthesis, AMP-activated protein kinase and phosphorylation state of translation factors in rat skeletal muscle.
Miranda L, Horman S, De Potter I, Hue L, Jensen J, Rider MH.
Pflugers Arch. 2008 Mar;455(6):1129-40. Epub 2007 Oct 24.
The AMP-activated protein kinase: more than an energy sensor.
Hue L, Rider MH.
Essays Biochem. 2007;43:121-37. Review.
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
Horman S, Vertommen D, Heath R, Neumann D, Mouton V, Woods A, Schlattner U, Wallimann T, Carling D, Hue L, Rider MH.
J Biol Chem. 2006 Mar 3;281(9):5335-40. Epub 2005 Dec 9.
Stress-induced activation of the AMP-activated protein kinase in the freeze-tolerant frog Rana sylvatica.
Rider MH, Hussain N, Horman S, Dilworth SM, Storey KB.
Cryobiology. 2006 Dec;53(3):297-309. Epub 2006 Sep 14.
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.
Woods A, Vertommen D, Neumann D, Turk R, Bayliss J, Schlattner U, Wallimann T, Carling D, Rider MH.
J Biol Chem. 2003 Aug 1;278(31):28434-42. Epub 2003 May 21.
Myocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2.
Horman S, Beauloye C, Vertommen D, Vanoverschelde JL, Hue L, Rider MH.
J Biol Chem. 2003 Oct 24;278(43):41970-6. Epub 2003 Aug 14.
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis.
Horman S, Browne G, Krause U, Patel J, Vertommen D, Bertrand L, Lavoinne A, Hue L, Proud C, Rider M.
Curr Biol. 2002 Aug 20;12(16):1419-23.
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia.
Marsin AS, Bertrand L, Rider MH, Deprez J, Beauloye C, Vincent MF, Van den Berghe G, Carling D, Hue L.
Curr Biol. 2000 Oct 19;10(20):1247-55.
2. Insulin and heart glycolysis
Evaluation of the role of protein kinase Czeta in insulin-induced heart 6-phosphofructo-2-kinase activation.
Mouton V, Vertommen D, Bertrand L, Hue L, Rider MH.
Cell Signal. 2007 Jan;19(1):52-61. Epub 2006 Jun 3.
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis.
Rider MH, Bertrand L, Vertommen D, Michels PA, Rousseau GG, Hue L.
Biochem J. 2004 Aug 1;381(Pt 3):561-79. Review.
Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B.
Bertrand L, Alessi DR, Deprez J, Deak M, Viaene E, Rider MH, Hue L.
J Biol Chem. 1999 Oct 22;274(43):30927-33.
Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades.
Deprez J, Vertommen D, Alessi DR, Hue L, Rider MH.
J Biol Chem. 1997 Jul 11;272(28):17269-75.
3. Mass spectrometry
The disulphide isomerase DsbC cooperates with the oxidase DsbA in a DsbD-independent manner.
Vertommen D, Depuydt M, Pan J, Leverrier P, Knoops L, Szikora JP, Messens J, Bardwell JC, Collet JF.
Mol Microbiol. 2008 Jan;67(2):336-49. Epub 2007 Nov 25.
Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei.
Vertommen D, Van Roy J, Szikora JP, Rider MH, Michels PA, Opperdoes FR.
Mol Biochem Parasitol. 2008 Apr;158(2):189-201. Epub 2007 Dec 23.
