De Duve Institute

Publications


Complete publication list (Pubmed search) :

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Representative publications :

Toffalini F, Demoulin JB.
New insights into the mechanisms of hematopoietic cell transformation by activated receptor tyrosine kinases.
Blood. 2010 Oct 7;116(14):2429-37. Review.

Medves S, Noël LA, Montano-Almendras CP, Albu RI, Schoemans H, Constantinescu SN, Demoulin JB.
Multiple oligomerization domains of KANK1-PDGFR{beta} are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.
Haematologica. 2011 Oct;96(10):1406-14.

Essaghir A, Toffalini F, Knoops L, Kallin A, van Helden J, Demoulin JB.
Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data (TFactS).
Nucleic Acids Res. 2010, 38:e120.

Medves S, Duhoux FP, Ferrant A, Toffalini F, Ameye G, Libouton JM, Poirel HA, Demoulin JB. KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia.
Leukemia 2010, 24:1052-55.

Toffalini F, Hellberg C, Demoulin JB.
Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein.
J Biol Chem. 2010, 285:12268-78.

Toffalini F, Kallin A, Michaux L, Vandenberghe P, Pierre P, Cools J and Demoulin JB.
The fusion proteins TEL-PDGFRβ and FIP1L1-PDGFRα escape ubiquitination and degradation.
Haematologica 2009, 94:1085.

Classen JF, Henrohn D, Rorsman F, Lennartsson J, Lauwerys BR, Wikström G, Rorsman C, Lenglez S, Franck-Larsson K, Tomasi JP, Kämpe O, Vanthuyne M, Houssiau FA, Demoulin JB.
Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis.
Arthritis Rheum
. 2009, 60:1137-44.
Supplementary material

Essaghir A, Dif N, Marbehant CY, Coffer PJ, Demoulin JB.
The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors. J Biol Chem (2009) 284:10334-42.
Microarray data: GEO #GSE14256