Thursday, March 1, 2018, at 17:00 in auditorium Lacroix
Lecture given by Professor David SABATINI
Whitehead Institute for Biomedical Research & Massachusetts Institute of Technology, Cambridge, MA, USA
Professor David Sabatini is a world-renowned cell biologist and biochemist. A Professor of Biology at the Massachusetts Institute of Technology, he is also a Member of the Whitehead Institute for Biomedical Research, as well as an Investigator of the Howard Hughes Medical Institute, a Senior Associate Member at the Broad Institute and a Member of the Koch Institute for Integrative Cancer Research. David Sabatini is known for his contributions to the study of the basic mechanisms that regulate cell growth and metabolism in mammals. A major focus of his lab is the Target of Rapamycin (TOR) pathway, a major regulator of growth in many eukaryotic species. This has resulted in the identification of many components of the pathway and to an understanding of their cellular and organismal functions, most of which have implications for diseases such as cancer and diabetes as well as in aging. He is also interested in the role of metabolism in cancer and in the mechanisms that control the effects of dietary restriction on tumorigenesis. Additionally, his lab has developed new technologies that facilitate the analysis of gene function in mammalian cells.
David Sabatini is a contributor to over 200 papers since he identified mTOR as a PhD student at Johns Hopkins University School of Medicine in 1994. He has received a number of awards, some of which are the 2014 NAS Award in Molecular Biology, the 2017 Lurie Prize in Biomedical Sciences, and the 2017 Dickson Prize in Medicine. He was elected to the U.S. National Academy of Sciences in 2016.