De Duve Institute

Endocytosis and epithelial differentiation


Group Leader
Pierre J. Courtoy
Christophe Pierreux

Contact
Pierre J. Courtoy
de Duve Institute and Université catholique de Louvain
CELL 75-41, 75 avenue Hippocrate
B-1200 Brussels
phone (direct) : 32 (0)2 764 75 69
phone (secretary) : 32 (0)2 764 75 41
fax : 32 (0)2 764 75 43
e-mail: Pierre Courtoy


Christophe Pierreux
de Duve Institute and Université catholique de Louvain
CELL 75-41, 75 avenue Hippocrate
B-1200 Brussels
phone (direct) : 32 (0)2 764 65 22
phone (secretary) : 32 (0)2 764 75 41
fax : 32 (0)2 764 75 43
e-mail: Christophe Pierreux


Group members >

Research topics

This group focuses on two topics related to the control of membrane trafficking : endocytosis and epithelial differentiation.

1. Endocytosis : Our goal is to better understand the regulation of membrane dynamics, both at distinct domains of the plasma membrane and during endocytic trafficking, using live cell and vital organ imaging by multiphoton microscopy, electron microscopy and subcellular fractionation.

2. Epithelial differentiation : This new project addresses the formation of epithelial tubules in developing pancreas and salivary glands, as complementary models of controlled opposite transitions between non-polarized cell masses and polarized epithelial monolayers.